GENOMIKA FANIDA AUTODOCK DASTURINI QOLLANILISHI VA IMKONIYATLARI

Mualliflar

  • Xoshimova Oqmonoy Andijon davlat universiteti
  • Dusmatova Gulbaxor Abdurashidovna Andijon davlat universiteti

Kalit so‘zlar:

Autodock, molekulyar docking, oqsil, ligand, bioinfarmatika, farmakologik, dokking algoritimlari.

Abstrak

AutoDock dasturi molekulyar doking asosida ishlovchi qulay vosita bo‘lib, genomika sohasida keng qo‘llaniladi. U oqsil-ligand bog‘lanishini modellashtirish, genetik mutatsiyalarning funksional ta’sirini aniqlash va yangi dori vositalarini ishlab chiqishda foydalidir. AutoDock dasturi bioinformatika va uch o‘lchamli modellashtirish vositalari bilan integratsiyada ishlaydi va shaxsiylashtirilgan terapiya yo‘nalishida keng imkoniyatlar yaratadi.

References

FORLI S. Computational protein–ligand docking and virtual drug screening with the AutoDock suite. Nature Protocols. 2016. 11(5). B. 905–919.

MORRIS G.M., HUEY R., OLSON A.J. AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility. Journal of Computational Chemistry. 2008. 30(16). B. 2785– 2791.

Trott O., Olson A.J. AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. Journal of Computational Chemistry. (2). B. 455–461.

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2025-06-23

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Jild 2 Nomeri 4.4 (2025): “Zamonaviy biologiyaning dolzarb muammolari va rivojlanish istiqbollari” mavzusida Xalqaro ilmiy-amaliy anjuman

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Copyright (c) 2025 Xoshimova Oqmonoy , Dusmatova Gulbaxor Abdurashidovna

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How to Cite

GENOMIKA FANIDA AUTODOCK DASTURINI QOLLANILISHI VA IMKONIYATLARI. (2025). Universal Xalqaro Ilmiy Jurnal, 2(4.4), 380-381. https://universaljurnal.uz/index.php/jurnal/article/view/2848