ANTI-RADICAL PROPERTIES OF GERANIIN POLYPHENOL.
Keywords:
Euphorbia franchetii, Geraniin polifen, antiradikal, spektrofotometrAbstract
The study of the molecular mechanisms of pathological conditions at the subcellular, including mitochondrial, level is one of the most urgent problems of our time. More than 90% of ATP required for cellular metabolism is synthesized by mitochondria. Therefore, mitochondria are a convenient target for several molecular groups, protecting them from cell damage and playing a key role in cytoprotective processes [Brand M.C. 2011]. In fact, mitochondria contain a large number of signaling pathways, which also provide control of cell proliferation, mitochondrial biogenesis, and cell death through oxidation-reduction reactions [Zadnipryany I. 2016]. Free radicals are chemical substances containing at least one unpaired electron in the outer shell, which usually give them high reactivity. The most common free radicals and reactive molecules in biological systems are oxygen (ROS) and nitrogen (NRs). ROS or NRs are formed during electron transfer reactions by losing or accepting electrons [Halestrap A.P 2015].
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