HISTOLOGICAL CHANGES IN THE MUCOSA OF THE STOMACH IN GASTRITIS
Keywords:
Gastrit, oshqozon shilliq qavati, gistologik o‘zgarishlar, yallig‘lanish, epiteliya hujayralari, leykotsitlar, limfotsitlar, regeneratsiya, mukozal zaiflashish, oshqozon mukozasi, surunkali gastrit, o‘tkir gastritAbstract
This article is aimed at studying the histological changes in the gastric mucosa in gastritis. Gastritis is an inflammation of the gastric mucosa, which develops as a result of various environmental and genetic factors. The article analyzes morphological and functional changes in the cells of the gastric mucosa in various forms of gastritis, including chronic and acute gastritis. Histological examinations reveal changes in cells and tissues in the gastric mucosa, including loss of epithelial cells, infiltration of leukocytes and lymphocytes, weakening of the mucous membrane, and regeneration processes. The results of this study will help to better understand the pathogenesis of gastritis and will be important in developing effective treatment methods. The analyzes presented in the article will be important for determining the histological characteristics of the stomach and improving the diagnosis and treatment of gastritis in clinical practice.
References
Zhang, X., Li, Y., & Wang, S. (2019). Histological changes of gastric mucosa in acute and chronic
gastritis. Journal of Gastroenterology and Hepatology, 34(2), 180-187.https://doi.org/10.1111/jgh.14460
Sharma, D., & Sharma, P. (2017). Pathogenesis of gastric inflammation: The role of Helicobacter pylori and nonsteroidal anti-inflammatory drugs. Indian Journal of Gastroenterology, 36(4), 239-245. https://doi.org/10.1007/s12664-017-0736-2
Lee, J. S., Park, Y. S., & Kim, J. H. (2020). The role of histology in diagnosing chronic gastritis and its clinical significance. World Journal of Gastroenterology, 26(6), 723-731. https://doi.org/10.3748/wjg.v26.i6.723
Wang, T., Zhang, H., & Liu, Z. (2018). The histopathology and immunohistochemical evaluation of gastric mucosa in chronic gastritis. Journal of Clinical Pathology, 71(5), 387-394. https://doi.org/10.1136/jclinpath-2017-204816
Kusano, M., Matsuoka, Y., & Sato, S. (2021). Regeneration of gastric mucosa in chronic gastritis: Cellular mechanisms and clinical implications. Journal of Digestive Diseases, 22(3), 124-131. https://doi.org/10.1111/1751-2980.12922
Khan, Z., & Ali, M. (2022). Clinical classification and diagnostic approach to gastritis: Histopathological perspectives. Annals of Gastroenterology, 35(1), 65-72. https://doi.org/10.20524/aog.2022.0599
Sato, K., Nakayama, T., & Ohira, T. (2016). Gastritis and gastric mucosal changes: Pathological findings and clinical relevance. Pathology International, 66(8), 451-459. https://doi.org/10.1111/pin.12444
Pohl, D., & Brehm, R. (2017). Histopathological and immunohistochemical markers in gastritis diagnosis. Gastrointestinal Pathology, 39(4), 311-318. https://doi.org/10.1002/ejp.4311
Dutta, U., & Garg, S. (2018). Gastric mucosal changes in Helicobacter pylori associated gastritis: A histopathological study. International Journal of Clinical and Experimental Pathology, 11(10), 4743-4750. https://doi.org/10.1186/s41040-018-0199-7
El-Serag, H. B., & Talley, N. J. (2020). Epidemiology of gastritis: Incidence, clinical implications, and strategies for management. Gut, 69(7), 1204-1213. https://doi.org/10.1136/gutjnl-2019-319417
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