NEUROTROPISM OF RABIES VIRUS AND MECHANISMS OF INFLUENCE ON THE CENTRAL NERVOUS SYSTEM
Keywords:
Quturish, rabies virus, neyrotropizm, asab tizimi, ensefalit, patogenez, neuroinfeksiya, Negri tanachalari.Abstract
This thesis provides a thorough analysis of the mechanisms of action of the rabies virus in the body,
in particular, how it spreads and damages the central nervous system. Scientifically based information is provided on the neurotropic properties of the virus, its migration through peripheral nerves, replication in nerve cells, and the pathomorphological changes it causes in brain tissue. The high mortality rate of the virus and the urgency of its early treatment are highlighted.
References
World Health Organization (WHO). Rabies Fact Sheets https://www.who.int
Murphy FA, Harrison AK. Rabies pathogenesis: Neurological routes and virus transport. J Virol. 2021.
Kumar V., Abbas A.K., Aster J.C. Robbins and Cotran Pathologic Basis of Disease, 10th Ed. Elsevier, 2020.
Fenner F., White DO, et al. Medical Virology, 4th Edition. Academic Press, 2013.
CDC – Centers for Disease Control and Prevention. Rabies: Pathogenesis and Clinical Signs – https://www.cdc.gov/rabies
Ryan K.J., Ray C.G. Sherris Medical Microbiology, 6th Ed. McGraw-Hill, 2014.
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