METHODS FOR EARLY DETECTION OF MELANOMA: BIOPSY AND MOLECULAR DIAGNOSTICS.
Keywords:
Molekulyar diagnostika,Genetik testlar,Patologik tekshiruv,Onkologiya,Mutatsiyalar,Individual davolash.Abstract
Melanoma is a highly invasive and malignant tumor, and its early detection is crucial for saving the patient's life. This article analyzes the role of biopsy and molecular diagnostics in the early diagnosis of melanoma. Biopsy is the main invasive diagnostic method, allowing for the detection of pathological changes and morphological assessment. However, it cannot fully reveal genetic features. Molecular diagnostics, on the other hand, allows for an in-depth study of genetic and biochemical changes and is an important tool for developing personalized therapy. Studies show that the combined use of biopsy and molecular diagnostics helps to more accurately diagnose melanoma and develop individual treatment strategies.
References
World Health Organization (WHO). (2023). Cancer: Melanoma of the Skin. Retrieved from www.who.int
Gershenwald, J. E., Scolyer, R. A. (2022). Melanoma Staging: Current Approaches and Future Directions. Journal of Clinical Oncology, 40(2), 155-167.
Curiel-Lewandrowski, C., et al. (2021). Early Detection of Melanoma: The Role of Dermoscopy and Molecular Diagnostics. Cancer Prevention Research, 14(1), 25-40.
Swetter, S. M., Tsao, H., Bichakjian, C. K. (2020). Guidelines for the Management of Primary Cutaneous Melanoma. Journal of the American Academy of Dermatology, 83(1), 89-108.
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