“THE EFFECT OF HUNGER ON THE NERVOUS SYSTEM”

Abstract

Effects of fasting on the nervous system. Fasting has a significant impact on the functioning of the nervous system, leading to changes in metabolism in the brain, affecting cognitive abilities and emotional state. When there is a shortage of nutrients, the body initially uses up glycogen reserves, and then proceeds to the processes of lipolysis and ketogenesis [1].
Prolonged fasting, in turn, entails an imbalance in the neurotransmitter system, which can manifest itself in memory loss, difficulty concentrating, anxiety, and depression. Moreover, chronic malnutrition is associated with an increased likelihood of developing neurodegenerative pathologies, which is caused by oxidative stress and disturbances in the functioning of the mitochondrial apparatus of cells. Although short-term periods of
fasting may have a neuroprotective effect by activating autophagy,
long-term nutrient deprivation has a negative impact on the
function of the central nervous system [2]. In-depth research into the mechanisms of
brain adaptation to starvation is necessary to develop effective approaches to
nutrition and the prevention of cognitive impairment.