LIGAND BINDING TO RECEPTORS
Keywords:
G-protein-coupled receptors (GPCRs), Ion channel receptors, receptor tyrosine kinases (RTKs), AutoDock Tools (ADT), molecular docking.Abstract
In living organisms, these interactions play an important role in cellular signaling, activation of metabolic pathways, and the production of pharmacological effects. The study used AutoDock software to identify and evaluate ligand-receptor binding. Using the program, various ligands were modeled by molecular docking with the target receptor and their binding energy, affinity, and location in the active sites were analyzed.
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