TECHNOLOGY FOR OBTAINING TETRACYCLINE FROM ACTINOMYCETES AND ITS SIGNIFICANCE IN BIOTECHNOLOGY
Keywords:
Tetracycline, antibiotic, actinomycetes, Streptomyces aureofaciens, Streptomyces rimosus, fermentation, biotechnology, extraction technologyAbstract
Tetracycline antibiotics have a broad spectrum of activity and play an important role in medicine and pharmaceuticals. The main producers are actinomycetes such as Streptomyces aureofaciens and Streptomyces rimosus. Optimal fermentation conditions, nutrient media composition, as well as methods of tetracycline extraction and purification represent the core stages of the biotechnological process. For large-scale industrial production of antibiotics, the development of high-yield strains and bioprocess optimization are crucial directions.
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Safin M.G., Ruziyev Yu.S., Aliqulov B.S. Biologik faol va dorivor moddalarning biotexnologiyasi. – Toshkent: Fan va texnologiya, 2019. – 320 b.
Aliqulov B.S. Mikrobiologiya va biotexnologiya asoslari. – Toshkent: Universitet, 2015. – 280 b.
Davranov K.D., Aliqulov B.S. Biotexnologiya. – Toshkent: Fan va texnologiya, 2022. – 340 b.
Madigan M.T., Martinko J.M., Bender K., Buckley D., Stahl D. Brock Biology of Microorganisms. – 14-th ed. – Boston: Pearson, 2015. – 1050 p.
Demain A.L., Sanchez S. Microbial drug discovery: 80 years of progress // The Journal of Antibiotics. – 2009. – Vol. 62, № 1. – P. 5–16.
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