THE EFFECT OF IONIZING RADIATION ON IMMUNITY

Authors

  • Boltaboyeva Gulsevar Boxodirjon qizi Andijon Davlat Universiteti
  • Abduqaxxorova Mukarramoy Azimjon qizi Andijon Davlat Universiteti
  • Xaqulova Muqaddas Shavkatovna Andijon Davlat Universiteti

Keywords:

Ionizing radiation; immunity; immunosuppression; lymphocytes; oxidative stress; DNA damage; inflammatory response.

Abstract

This thesis analyzes the effects of ionizing radiation on the human immune system based on scientific literature and experimental studies. The effects of low, medium and high doses of radiation on the dynamics of immune cells, inflammatory processes, hematopoietic system activity and changes in the immune response are highlighted. The mechanisms of immunosuppressive or immunostimulatory action of radiation, the molecular basis of processes associated with oxidative stress and DNA damage are also discussed. The results of the study are important for assessing the health of individuals working with ionizing radiation, improving the safety of medical radiology and developing immunoprotective strategies.

References

Murtazayeva N.K. «Radioaktiv elementlarning immun tizimiga salbiy ta'sirini baholash». Samarqand davlat tibbiyot universiteti, Biologik kimyo kafedrasi.

Isroilova Sevarxon Ikromjon qizi, Aliyeva Mushtariy, Usmonova Guliruxsor. «Radiaktiv nurlarning inson organizmiga ta'siri». Jurnal: «Лучшие интеллектуальные исследования», 2025.

Qurbonov A., Qurbonova B., Abdurashidova D. «Radiatsiyaning odamlarga ta'siri». Jurnal: «Физико‑технологического образование», 2022.

Carvalho HA, Villar RC. Radiotherapy and immune response: the systemic effects of a local treatment. Clinics (São Paulo). 2018;73(Suppl 1):e557s.

Hussien SM. Immune system modulation by low-dose ionizing radiation. [Jurnal: 2023].

Published

2025-12-11

How to Cite

THE EFFECT OF IONIZING RADIATION ON IMMUNITY. (2025). Universal International Scientific Journal, 2(12), 86-88. https://universaljurnal.uz/index.php/jurnal/article/view/3795