CRISPR/CAS9 TEXNOLOGIYASI BILAN SARATON KASALLIGINI DAVOLASH
Kalit so‘zlar:
Genetik tahrir, gen terapiyasi, immunoterapiya, onkogenez, genomni manipulyatsiya qilish, molekulyar biotexnologiyaAbstrak
Ushbu maqolada CRISPR-Cas9 texnologiyasining saraton kasalligini davolashdagi
imkoniyatlari,uning qanday ishlash mexanizmlari keltirilgan. Maqola, CRISPR-Cas9 tizimining
genomni aniq tahrirlash imkoniyatlarini, uning saraton kasalligi uchun terapiya sifatida qanday
ishlatilishi mumkinligini yoritib beradi. Texnologiyaning genetik manipulyatsiya, gen
terapiyasi,immunoterapiya sohalarida qo‘llanilishi, shuningdek, saraton hujayralarini aniqlash va
yo‘q qilishdagi yutuqlari muhokama qilinadi.
References
Jinek, M., & Doudna, J. A. (2012). A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity. Science, 337(6096), 816-821. https://doi.org/10.1126/science.1225829
Zhang, F., Wen, Y., & Guo, X. (2014). Crispr/Cas9 for Genome Editing: Progress, Implications, and Applications. Journal of Human Genetics, 59(6), 342-349. https://doi.org/10.1038/jhg.2014.30
Sander, J. D., & Joung, J. K. (2014). CRISPR-Cas Systems for Editing, Regulating and Targeting Genomes. Nature Biotechnology, 32(4), 347-355. https://doi.org/10.1038/nbt.2842
Zetsche, B., Gootenberg, J. S., & Abudayyeh, O. O. (2015). Crispr-Cas9 Genome Editing in Human Cells: A Practical Guide. Trends in Biotechnology, 33(4), 293-299. https://doi.org/10.1016/j.tibtech.2015.02.003
Ma, H., & Zhang, L. (2019). CRISPR/Cas9-based Genome Editing: The Role of Targeted DNA Repair in Cancer Therapy. Cancer Research, 79(10), 2680-2689. https://doi.org/10.1158/0008-5472.CAN-18-3413
Downloads
Nashr qilingan
Nashr
Bo'lim
License
Copyright (c) 2025 Qo‘chqorxo‘jayev Saidburxon
This work is licensed under a Creative Commons Attribution 4.0 International License.
(+998)90 142-39-38
Andijon viloyati, Marhamat tumani, Qashqar ko’chasi 189-uy