NEUROMYELITIS OPTICA (DEVIC SINDROMI): ZAMONAVIY DAVOLASH YONDASHUVLARI

Mualliflar

  • Sodiqov Sardorbek Maxmudjon o`gli Kokand Universiteti Andijon filiali

Kalit so‘zlar:

Neuromyelitis optica (NMO), NMOSD, Devic sindromi, Multiple skleroz (MS), AQP4-antitanalar (AQP4-Ab), Immunosupressiv terapiya, Plazmaferez (PLEX), Azatioprin, Metilprednizolon, Autoimmun kasallik, Markaziy asab tizimi.

Abstrak

Neuromyelitis optica (NMO), shuningdek, Devic sindromi nomi bilan tanilga
va uning kengroq spektriga oid kasalliklar (NMOSD – neuromyelitis optica spectrum disorders)
markaziy asab tizimining autoimmun kasalliklari guruhiga kiradi. Ushbu kasallik ko‘rish nervlari,
orqa miya, miyastabani va kamdan-kam hollarda miya supratentorial sohalarini zararlaydi. Bazan
Multiple Skleroz (MS) bilan ham chalkashib ketishi mumkin. Ushbu maqolada NMO va uning
zamonaviy davolash yo‘nalishlari, xususan, immunosupressiv terapiya va plazmaferezning klinik
qo‘llanilishi ko‘rib chiqiladi. Maqola tahliliy yondashuv asosida yozilgan bo‘lib, mavjud klinik
ma'lumotlarga asoslanadi.

References

Petra Nyotrova a kol. Neuromyelitis optica a onemocneni jejiho sirsiho spectra. 2024. 1

Jarius S , Wildemann B . The history of neuromyelitis optica . J Neuroinflammation 2013 ; 10 : 8

Lennon VA , Wingerchuk DM , Kryzer TJ et al . A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis . Lancet 2004 ; 364 : 2106 – 12 .

Cree BA, Goodin DS, Hauser SL. Neuromyelitis optica. Semin Neurol 2002; 22: 105–22.

Weinshenker BG. Neuromyelitis optica: what it is and what it might be. Lancet 2003; 361: 889–90.

Akaishi T., Nakashima I. The treatment of neuromyelitis optica: present and future perspective //J. Neurol. Disord. Stroke. – 2014. – Т. 2. – С. 1076.

Agre, P. The aquaporin water channels. Proc Am Thorac Soc 2006, 3, 5-13.https://doi.org/10.1513/pats.200510-109JH.

Kong, W.; Yang, S.; Wang, Y.; Bendahmane, M.; Fu, X. Genome-wide identification and characterization of aquaporin gene family in Beta vulgaris. Peer J. 2017, 5, e3747. https://doi.org/10.7717/peerj.3747.

Zhang, L.; Chen, L.; Dong, H. Plant aquaporins in infection by and immunity against pathogens- A critical review. Front. Plant. Sci 2019, 10, 632. https://doi.org/10.3389/fpls.2019.00632.

Hafler DA, Slavik JM, Anderson DE, O‘Connor KC, De Jager P, Baecher-Allan C. Multiple sclerosis. Immunological Reviews 2005;204:208-31.

Compston A, Confavreux C, Lassman H, McDonald I, Miller D, Noseworthy J. The story of multiple sclerosis. McAlpine’s Multiple Sclerosis. Philadelphia: Churchill Livingstone Elsevier, 2006:3.

Hafler DA, Slavik JM, Anderson DE, O‘Connor KC, De Jager P, Baecher-Allan C. Multiple sclerosis. Immunol Rev 2005;204:208-31.

İdiman E. Multipl Skleroz'un immunopatogenezi. Turkiye Klinikleri J Neur 2004;2;171-176.

Conrad A, Coenen M, Schmalz H, Kesselring J, Cieza A. Validation of the comprehensive ICF core set for multiple sclerosis from the perspective of physical therapists. Phys Ther. 2012;92:799-820.

Coenen M, Cieza A, Freeman J, Khan F, Miller D, Weise A, et al. The development of ICF Core Sets for multiple sclerosis: results of the International Consensus Conference. J Neurol. 2011;258:1477-88.

Elion, G.B. 1993. The George Hitchings and Gertrude Elion Lecture. The pharmacology of azathioprine. Ann. N. Y. Acad. Sci. 685:400–407.

Farmakologiya asoslari. (2007). M.N.Mahsumov, X.Aliyev, M.A.Odilov, N.A.Musayeva. 283.

Wingerchuk, D. M., Lennon, V. A., Pittock, S. J., Lucchinetti, C. F., & Weinshenker, B. G. (2007). The spectrum of neuromyelitis optica. The Lancet Neurology, 6(9), 805–815. https://doi.org/10.1016/S1474-4422(07)70216-8

National Institutes of Health (NIH). (2012). Methylprednisolone for inflammatory demyelinating diseases. Retrieved from

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422147/20. Jacob, A., & Weinshenker, B. G. (2008). An approach to the diagnosis of acute transverse myelitis. Seminars in Neurology, 28(1), 105–120. https://doi.org/10.1055/s-2007-1019139

National Institutes of Health (NIH). (2012). Methylprednisolone for inflammatory demyelinating diseases. Retrieved from

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422147/

M. E. Brecher, “Plasma exchange: why we do what we do,” Journal of Clinical Apheresis, vol. 17, no. 4, pp. 207–211, 2002.

Bonnan M., Cabre P. Plasma exchange in severe attacks of neuromyelitis optica //Multiple sclerosis international. – 2012. – Т. 2012. – №. 1. – С. 787630.

Downloads

Nashr qilingan

2025-06-16

How to Cite

NEUROMYELITIS OPTICA (DEVIC SINDROMI): ZAMONAVIY DAVOLASH YONDASHUVLARI. (2025). Universal Xalqaro Ilmiy Jurnal, 2(4.5), 720-723. https://universaljurnal.uz/index.php/jurnal/article/view/2571