"ZEBRA BALIQ (DANIO RERIO): BIOLOGIK XUSUSIYATLARI VA ILMIY TADQIQOTLARDAGI O‘RNI"
Kalit so‘zlar:
Zebra baliq, Gen, DNK, model, regeneratsiya, mutatsiya, farmatsevtika, biobid, fin, retina.Abstrak
Zebra baliq (Danio rerio) so‘nggi yillarda biologiya va tibbiyot sohalarida eng ko‘p o‘rganilayotgan model organizmlardan biriga aylangan. Ushbu kichik chuchuk suv baliqlari, o‘zining oddiy tashqi ko‘rinishiga qaramay, odam genlarining taxminan 70 foizini o‘zida aks ettiradi. Bu ularga inson organizmi kasalliklarini chuqur o‘rganishda juda muhim vosita sifatida qarash imkonini beradi. Zebra baliqlarining embrionlari tashqi muhitda rivojlanishi va ularning shaffofligi, genetik manipulyatsiyani soddalashtiradi. Ushbu baliqning yurak, ko‘z, suyak va boshqa a’zolarini regeneratsiya qilish qobiliyati esa regenerativ tibbiyotda katta istiqbollar ochmoqda. Shuningdek, zamonaviy Kontrakt Tadqiqot Tashkilotlari (CRO), jumladan Biobid kompaniyasi tomonidan dori moddalari va kasalliklar modellarini sinashda keng qo‘llanilmoqda. Ushbu tezisda zebra baliqning biologik xususiyatlari, ilmiy tadqiqotlardagi o‘rni hamda inson salomatligiga ta’siri chuqur tahlil qilinadi.
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