Qo'rg'oshin bilan zaharlanish va yog'li dieta bo'yicha kalamushlarda qandli diabet modelini ko'rsatish
Kalit so‘zlar:
kalamush, qo'rg'oshin, og'ir metallar, safro, organizm, zaharli moddalar, ksenobiotiklar, 2-toifa diabet, atrof-muhit, qon, glyukoza, jigar, glikogenAbstrak
To'g'ridan-to'g'ri yoki bilvosita tanaga kiradigan og'ir metallarning to'planishi natijasida yuzaga keladigan patologik sharoitlar alohida qiziqish uyg'otadi. Ushbu tadqiqotda og'irligi 210-220 gramm bo'lgan erkak oq kalamushlarga 28 hafta davomida 0,05 mg / kg qo'rg'oshin tuzi bo'lgan suv berildi va bu vaqt davomida yuqori yog'li parhez bilan oziqlandi. Hayvonlarning qonidagi glyukoza miqdori tajribaning 7, 14, 21 va 28-haftalarida tekshirildi. Uning ma'lumotlariga ko'ra, qondagi glyukoza miqdori 7 haftada 39,1 foizga, 14 haftada 60,7 foizga va 21 haftada deyarli 2,5 barobarga oshgani aniqlandi. 28-haftaga kelib, qondagi glyukoza darajasi deyarli 3,5 baravar ko'payganligi kuzatildi, nazorat guruhidagi indeks 5,2 mmol / l va eksperimental guruhda - 18,2 mmol / l ni tashkil etdi.
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