EFFECT OF ULTRASONOGRAPHY ON FETAL RED BONE MARROW

Authors

  • Топилова Феруза Махаммадовна Andijon davlat universiteti
  • Кимсанова Гулнора Абдурашидовна Andijon davlat universiteti
  • Кимсанова Гулнора Абдурашидовна Andijon davlat universiteti
  • Абдуллаева Саида Асилбек кизи Andijon davlat universiteti
  • Мухторов Фирдавс Тохиржон угли Andijon davlat universiteti

Keywords:

Ultrasound, fetal bone marrow, hematopoiesis, obstetric diagnostics, biophysical effects, hematopoietic stem cells.

Abstract

Ultrasound diagnostics (US) is a standard of obstetric practice, but its biophysical effects, including thermal and mechanical effects, raise questions about safety for fetal tissues, including red bone marrow. This review systematizes data on the physical and biological basis of ultrasound, the characteristics of fetal hematopoiesis, and clinical safety. Experimental studies indicate potential subcellular effects of ultrasound on hematopoietic stem cells at high-intensity parameters.

References

Miller DL, Smith NB, Bailey MR, et al. Bioeffects considerations for diagnostic ultrasound. J Ultrasound Med. 2018;37(1):77-94. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767717/

Salvesen KA, Lees C. Ultrasound safety in early pregnancy: The evidence base. Best Pract Res Clin Obstet Gynaecol. 2019;58:82-91. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698997

Bigelow TA, Church CC, Sandstrom K. Ultrasound bioeffects and safety considerations. Ultrasound Med Biol. 2019;45(7):1553-1565. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599632/

Zhu AZ, Ma Z, Wolff EV, et al. HES1 is required for mouse fetal hematopoiesis. Stem Cell Res Ther. 2024;15(1):235. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11327845

Boueya IL, Sandhow L, Albuquerque JRP, et al. A specialized bone marrow microenvironment for fetal haematopoiesis. Leukemia. 2025;39(1):8-24. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10786890/

Stratmeyer ME, Greenleaf JF, Dalecki D. Fetal ultrasound: Mechanical effects. J Ultrasound Med. 2020;39(6):1045-1056. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317529/

Li G, Yang N, Xie M, et al. Perinatal and follow-up outcome study of fetal anomalies with multidisciplinary consultation. Ther Clin Risk Manag. 2017;13:1303-1307. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633289/

Duck FA. Ultrasound exposure and the developing fetus: A review of safety. Ultrasound. 2017;24(4):192-200. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715406/

Холмирзаева, М., Топилова, Ф., Абдуллаев, А. А., & Мирзабеков, И. А. (2016). ФИЗИОЛОГИЧЕСКИЕ ИЗМЕНЕНИЯ ОРГАНИЗМА ЮНЫХ ПЛОВЦОВ В ЗАВИСИМОСТИ ОТ ФИЗИЧЕСКИХ НАГРУЗОК. Современные тенденции развития науки и технологий, 116.

Mushtariy Kushaqboeva, ., Madinakhan Kholmirzaeva, ., & Feruza Topilova, . (2023). DESCRIPTION OF PHYSICAL DEVELOPMENT INDICATORS OF PRIMARY CLASS BOYS OF ANDIJAN REGION. International Journal of Medical Sciences And Clinical Research, 3(04), 19–27. https://doi.org/10.37547/ijmscr/Volume03Issue04-03

Firdavs, M., Feruza, T., Gulnora, K., & Gulmira, Y. (2024). LIVING AND DEAD WATER MYTH OR REALITY. Frontline Medical Sciences and Pharmaceutical Journal, 4(04), 17-23.

Топилова, Ф. М., & Кимсанова, Г. Влияние физических нагрузок на показатели физическо-го развития детей и подростков. Министерство высшего и среднего специального образования республики Узбекистан Каракалпакский государственный университет имени бердаха Факультет биологии, 96.

Downloads

Published

2025-06-23

How to Cite

EFFECT OF ULTRASONOGRAPHY ON FETAL RED BONE MARROW. (2025). Universal International Scientific Journal, 2(4.4), 639-642. https://universaljurnal.uz/index.php/jurnal/article/view/2944