NEUROPSYCHOLOGICAL AND NUTRITIONAL MODULATORS OF CANCER IMMUNITY: A COMPREHENSIVE PERSPECTIVE IN IMMUNO-ONCOLOGY
Keywords:
Immuno-onkologiya, surunkali stress, o'sma immuniteti, neyroimmunologiya, CAR-T terapiyasi, GMO, ichak mikrobiotasi, psixologik stress, immunitetni bostirish, saraton mikromuhitiAbstract
Immuno-oncology, an evolving domain of cancer research, leverages the immune system’s ability to recognize and eliminate malignancies. Despite promising advances such as immune checkpoint inhibitors and CAR-T cell therapy, treatment efficacy varies significantly among patients. Emerging studies reveal that the host's psychological state and dietary exposures, particularly to genetically and chemically modified foods, can alter immune responses, influence tumor progression, and mediate treatment outcomes. This article provides a comprehensive academic synthesis of current literature regarding the neuropsychological and nutritional influences on tumor immunity. A multidimensional “neuro-psycho-immunological model” of cancer is proposed, linking chronic stress, altered gut microbiota, and immune suppression to the tumor microenvironment. This interdisciplinary analysis suggests a paradigm shift: cancer is not solely a genetic or cellular phenomenon, but an integrative systemic disease influenced by environmental and behavioral inputs. Such insight may lead to more personalized, preventive, and holistic therapeutic strategies in modern oncology
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