CHEMICAL COMPOSITION OF BLACK SEDANA, USE IN FOLK MEDICINE AND MODERN MEDICINE
Keywords:
Black cumin, thymoquinone, bioactive substance, folk medicine, modern medicine, medicinal plants, pharmacological properties, antioxidant, anti-inflammatory effect, natural medicine, health care, scientific research.Abstract
This article scientifically analyzes the chemical composition of the black salvia plant, its role in folk medicine, and its use in modern medicine. The positive effects of the bioactive substances contained in the plant — thymoquinone, nigellone, carvacrol, thymohydroxyquinone, p-cymene, and other compounds — on human health are highlighted. The article compares the experiences of folk medicine and modern medicine, and analyzes the effects of black salvia on inflammation, cancer, diabetes, liver, and cardiovascular diseases based on scientific sources. In addition, recommendations are developed on the benefits of black salvia as a natural medicine, innovative research in the pharmaceutical field, and the possibilities of its widespread use in medical practice in the future.
References
Mahmood, K., et al. (2013). Nigella sativa: A Comprehensive Review of Its Therapeutic Potential. PMC. https://www.ncbi.nlm.nih.gov/articles/PMC11677364/ PubMed Central
Yimer, E. M., et al. (2019). Nigella sativa and its potential role in medical therapy. Journal of Evidence-Based Integrative Medicine, 24, 1–15. PubMed Central
Shakeri, F., Khazaei, M., & Boskabady, M. H. (2018). Cardiovascular effects of Nigella sativa L. and its constituents. Indian Journal of Pharmaceutical Sciences, 80(6), 971-983. https://www.researchgate.net/publication/330246711_Cardiovascular_Effects_of_Nigella_Sativa_L_and_its_Constituents ResearchGate
Maheswari, K. U. (2022). A review on hypo-cholesterolemic activity of Nigella sativa. PMC
Traditional and modern usage of Nigella sativa L. (Black cumin)
Dalli, M., Daoudi, N. E., Azizi, S.-e., Roubi, M., Alami Merrouni, I., Souna, F., Choukri, M., Kim, B., & Gseyra, N. (2025). Harnessing the Hepatoprotective and Nephroprotective Potential of Nigella sativa Fractions via per os Administration in CCl₄-Intoxicated Wistar Rats: A Mixed Approach. Pharmaceuticals, 18(8):1147. https://doi.org/10.3390/ph18081147 MDPI
Frontiers. (2023). Mechanism of the antidiabetic action of Nigella sativa and its therapeutic potential in diabetes mellitus management. Frontiers in Nutrition. https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2023.1126272/full Frontiers
Oncotarget. (2015). Thymoquinone, as an anticancer molecule: from basic research to clinical applications. Oncotarget. https://www.oncotarget.com/article/17206/text/ Oncotarget
Badar, A., et al. (2017). Effect of Nigella sativa supplementation on lipid profile, blood pressure and heart rate in type 2 diabetic patients. Translational Medicine
PMC (2023). Potential anticancer properties and mechanisms of thymoquinone in colorectal cancer: A review. PMC
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