SOME HYDROLYZABLE TANNINS SMOOTH RAT AORTA DESCRIPTION OF THE EFFECT OF VASORELAXANT ON MUSCLE

Authors

  • Аzizbek Mutalipov Andijan State University
  • Аnvar Zaynabiddinov Andijan Institute of Economics and Construction
  • Po`lat Usmanov Institute of Biophysics and Biochemistry under UzMU
  • Raxmatillo Raximov Academician O.S. Sodikov of the UzR FA Institute of Bioorganic Chemistry
  • Shaxriyor Jo‘raboyev Andijan State University

Keywords:

aortic smooth muscle, hydrolyzable tannins,, vasorelaxant, ion channels, verapamil

Abstract

According to available data, the normal function of blood vessels is ensured
by the activity of various ion transport systems located in the membrane of blood-vascular
smooth muscle cells and in the sarcoplasmic reticulum [1,2]. It was noted that potentialdependent Ca2+
-channels located in the plasmalemma play an important role, and Ca2+-
transport systems are one of the central components in the contraction function of smooth
muscle cells [3]. Taking into account the above information, the purpose of this research work
is to study the mechanism of relaxant effect of 2,3-di-O-galloyl--d-glucose (GT-3)
hydrolyzable tannin.

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Published

2024-06-24

Issue

Vol. 1 No. 4 (2024): Scientific and practical republican on the topic "Actual problems, innovations and prospects of the sciences of human physiology and life activity safety" Proceedings of the conference

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Articles

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Copyright (c) 2024 Mutalipov Аzizbek Аbdullajon oʼgʼli, Zaynabiddinov Аnvar Erkinjonovich, Usmanov Po`lat Bekmuratovich, Raximov Raxmatillo Nurallievich, Jo‘raboyev Shaxriyor G’ayratbek o‘g’li

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How to Cite

SOME HYDROLYZABLE TANNINS SMOOTH RAT AORTA DESCRIPTION OF THE EFFECT OF VASORELAXANT ON MUSCLE. (2024). Universal International Scientific Journal, 1(4), 114-116. https://universaljurnal.uz/index.php/jurnal/article/view/465