THE ROLE OF OXIDATIVE PHOSPHORYLATION IN MITOCHONDRIA IN CELL VIABILITY
Keywords:
Oxidative phosphorylation, mitochondria, cellular energy, circadian rhythms, aging, biological clock.Abstract
The work is devoted to the study of the role of oxidative phosphorylation (OP) in maintaining cell viability. A hypothesis is proposed that increasing the efficiency of OP in mitochondria can contribute to prolongation of cell life and stabilization of circadian rhythms. The mechanisms linking energy metabolism with the expression of "clock" genes and aging are discussed. The importance of mitochondrial metabolism as a potential target in the therapy of age-related and metabolic disorders is emphasized.
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