Spectrophotometric determination of glycyrrhizic acid and flavonoids content of "FERRAKON" BFQ

Authors

  • Asqarov Ibrohim Rahmonovich
    Andijan State University
  • Isaev Yusup Tojimamatovich
    Andijan State University
  • Rustamov Sanjar Ashiraliyevich
    Andijon davlat universitet
  • Egamberdiyev Dostonbek Usmonjon o’g’li
    Andijan State University

DOI:

https://doi.org/10.69891/3060-4540.2024.1.1.001

Abstract

In this research work, the main active substance - glycyrrhizic acid and flavonoids in the "FERRAKON" biologically active supplement (BFQ) containing licorice root extract, developed by local manufacturers, was determined by spectrophotometric method. the results of the experiments are presented. It was found that the amount of glycyrrhizic acid in BFQ is 3.78%, and the amount of flavonoids is 9.97%.

Keywords:

licorice root biologically active compounds, flavonoids pinocembrin standardization spectrophotometry

References

Куркин В.А., Егоров М.В. Стандартизация корней солодки голой и лекарственного препарата «солодки экстракт жидкий» // Фундаментальные исследования. – 2014. – №6-6. – С. 1232-1236; URL: https://fundamental-research.ru/ru/article/view?id=34320 (дата обращения: 05.07.2024).

Askarov, I.R., Rustamov, S.A., Egamberdiev, D.U., Isaev, Yu.T. & Kushiev, Kh.Kh. (2021). Molecular complexes of monoammonium salt of glycyrrhizic acid with some urea and their antibiotic activity. Chemical Problems, (3), 160-167.

Исаев Ю.Т., Рустамов С.А., Эгамбердиев Д.У., Абдуллаев М.Н., Аскаров И.Р., “Фотометрическое определение глицирризиновой кислоты в сухих корнях солодки”. Вестник Пермской государственной фармацевтической академии. Сборник материалов (22 апреля 2021 года). 149-151 c.

М.В.Егоров, В.А.Куркин, Г.Г.Запесочная, В.А.Быков. Качественный и количественный анализ сырья и препаратов солодки. Вестник ВГУ. Серия: Химия, Биология. Фармация. 2005. №1. С.175-180.

ФС 2.5.0040.15 «Солодки корни». ГФ РФ ХIV, т.IV, М., 2018 – c.6429.

Askarov, I., Isaev, Y., Tashtemirova, G., Rustamov, S., Kadirov, M., & Shadmanov, K. (2023). Synthesis of complex compounds of the monoammonium salt of glycyrrhizic acid and thiourea. In E3S Web of Conferences (Vol. 383, p. 04023). EDP Sciences.

Ren CA, Li YX, Cui JY, Sheng ZX, Ran XH, Wang BH, Zhang MH. Efficacy of glycyrrhizin combined with cyclosporine in the treatment of non-severe aplastic anemia. Chin Med J (Engl). 2013;126(11):2083-6. PMID: 23769562.

Lesjak M, K S Srai S. Role of Dietary Flavonoids in Iron Homeostasis. Pharmaceuticals (Basel). 2019 Aug 8;12(3):119. doi: 10.3390/ph12030119. PMID: 31398897; PMCID: PMC6789581.

Maryam Mazhara, Shaheen Faizib, Anum Gula, Nurul Kabira and Shabana U. Simjee., «Effects of naturally occurring flavonoids on ferroportin expression in the spleen in iron deficiency anemia in vivo», RSC Advances., Issue 38, 2017, RSC Adv., 2017,7, 23238-23245 https://doi.org/10.1039/C7RA02138K

Published

How to Cite

Asqarov, I., Isaev, Y., Rustamov, S., & Egamberdiyev, D. (2024). Spectrophotometric determination of glycyrrhizic acid and flavonoids content of "FERRAKON" BFQ. Universal International Scientific Journal, 1(4), 3–6. https://doi.org/10.69891/3060-4540.2024.1.1.001

Similar Articles

1 2 3 4 > >> 

You may also start an advanced similarity search for this article.