Vol. 1 No. 4 (2024): Scientific and practical republican on the topic "Actual problems, innovations and prospects of the sciences of human physiology and life activity safety" Proceedings of the conference

In the article, involving children in sports activities, children's health
the importance of sports training elements in its development is discussed.

To make the growing young generation physically healthy and mentally strong
a lot of work is being done in our country today. Especially a girl
studying the organism is a health-prophylactic in determining the health of the next generation
measures are important in determining measures. This is why children in our country
to develop sports, women's and girls' sports, to organize a healthy lifestyle among the population
has been paying great attention to volunteer work

Avitaminosis or hypovitaminosis is a very common problem. Vitamin
deficiency occurs as a result of the influence of environmental factors, lack of vitamins
necessary for the body, improper nutrition. This thesis provides information on the types of
vitamins and what pathological conditions occur in the body when they are lacking, as well as
preventive measures for vitamin deficiency.

In this thesis, we consider the roles of fats in the human body, including their
biological functions, classification, sources in the diet, effects on health, as well as
recommendations for rational consumption.

Antioxidants play an important role in maintaining human health by
preventing oxidative stress and protecting cells from damage. Their importance is associated
with the prevention of various diseases such as cancer, cardiovascular diseases and premature
aging. This abstract discusses the importance of antioxidants in the human body and their
impact on overall health.

There are two types of wrestling on the territory of our republic, wrestling with
the rules of Bukhara and Fergana. National sports, in particular, appear not as unique elements
of the national culture of each nation, but as an important means of solving the current tasks
of physical activity. Everyone must have seen wrestlers trying their best during Spartakiads.
Popular wrestlers with high physical characteristics and technical skills are called wrestlers.
Wrestling is a constant companion of all celebrations.

This article talks about the attention paid to sports for the future of the young
generation in our country, and this information is explained with the help of relevant literature.

: Modern technology has revolutionized the field of education and their
Integrating biology lessons into student learning and engagement with the subject
able to change methods. This scientific article organizes biology lessons
effective use of modern technologies in education, their students
activity, impact on conceptual understanding and practical application of biological concepts
attention is drawn. It is related to the use of modern technologies in biology education
exploring the benefits and challenges, this article is about their successful implementation
provides insight and creates a dynamic and immersive learning experience for teachers
gives recommendations on optimizing their use.

In this article, it is explained that the state administration bodies, local state
authorities, citizens' self-government bodies, public associations, enterprises, institutions and
organizations, officials, as well as citizens assist and provide the necessary assistance to the
state bodies implementing the fight against terrorism. It is considered that the leadership and
management of an anti-terrorist operation should be determined in each specific case, taking
into account the threat of terrorist acts and the extent of the danger.

Today, in the field of "Basics of Life Safety", various scientific researches
on the development of the educational system based on an innovative approach, innovative
management of educational processes at different levels or stages, and a number of works are
carried out in the field of training teachers for innovative activities. is going

Safety of activity from ancient times to the present day
is one of the most important aspects of scientific and practical interests of mankind. Everyone is human
always strives to ensure his safety. With the development of production, it is
issues require special knowledge. In our time, security problems are more
intensified. It is known that accidents, fires, accidents and losses are bigger
will be damaged.

In this article, the blood in the body moves in a closed circle, and the large and
small blood circulation circle is distinguished. The large blood circulation circle provides blood
flow between the heart and the organs, and flows from the left ventricle of the heart through
the aorta artery arteriole tissue and 2 vena cava to the right part of the heart. From the right
ventricle of the heart, 2 pulmonary arteries enter the lungs, and 4 pulmonary veins leave the
lungs and flow into the left ventricle of the heart.

antioxidant and cardioprotective properties of Rhus glabra polyphenol fraction
extract, presence of substances with flavonoid structure, gallic acid and its derivatives were
determined. This makes it possible to use it to obtain an effective and safe tool with
simultaneous cardioprotective and antioxidant effects for the treatment and prevention of
cardiovascular diseases. The results of this study allow the use of Rhus glabra to create an
over-the-counter drug for the prevention and complex treatment of various cardiovascular
diseases. All the above-mentioned biologically active substances of plants belonging to this
species can serve as a basis for assuming that they have a wide range of pharmacological
effects - they have cardioprotective, antioxidant, immunomodulatory, antitoxic, antitumor and
other properties. The human body has a system of protection against the harmful effects of
oxygen radicals. However, in a number of pathological diseases, this system of the body cannot
cope with the massive release of oxygen radicals. Therefore, antioxidants have been used in
the treatment of various cardiovascular diseases to affect free radical oxidation

Currently, in the conditions of ischemia, the intensity of peroxide oxidation of
lipids of the heart mitochondria membrane increases, ATF synthesis decreases, antioxidant
enzyme activities change, and mPTP permeability increases [3]. However, in the conditions of
experimental ischemia, SFL isolated from the plant Crocus sativus L. belonging to the family
Iridaceae and Alhagi canescens (Regel) belonging to the family Fabaceae (Leguminosae) B.
Keller & Shap. The effects of flavonoids isolated from the plant Narcissin have not been
studied.

In Uzbekistan, national wrestling is a situational sport, as it is represented by
rapidly changing situations that occur during the competition, and the influence of distractions
arising from an active conflict with the opponent is also significant. Since 2000, significant
works of scientists and researchers of our country have appeared in the press, they are not only
of theoretical and practical importance, but also help to increase the position of wrestling in
the international sports field. In 2005, uniform rules for belt wrestling were established.

A whole team of scientists, specialized scientific and educational institutions
have effectively worked to solve the problems of physical education. The abundance of
practical material and the discovery of new patterns led to the differentiation of the theory and
methodology of the first unified physical education. New special disciplines “Organization and
management of physical culture”, “Biomechanics of exercises”, “Sports psychology”, “Sports
metrology”, “Sports physiology”, “Therapeutic physiotherapy”, “Physical hygiene”,
“Valeology” and others

Students are introduced to the experiences gained in the use of
information technology tools in the teaching of biology, their material base, didactic
features, and the methodology of their use in the educational process. In this sense, this
article focuses on the mechanisms of introducing and effectively using digital
educational tools to improve the effectiveness of the educational process.

This article highlights issues of the development of modern medicine, in
particular biomedicine, characterizes the rapid development of genetic engineering, cellular,
tissue and immunobiological technologies in medicine, indicates ideas about methods of
treating the most dangerous diseases - autoimmune, oncological, infectious, etc.

In the modern world, the issues of ensuring the safety of the individual, as
well as the life of the entire society, are increasing. The scientific basis is a general theory of
security. Being a serious problem for today and using many other disciplines to solve it, life
safety has developed its own terminology, conceptual schemes, theoretical foundations, and
research methods.

The effect of athletic gymnastics exercises on the general character and local (muscle
group, muscles and skeletal system). So athletic
Gymnastics exercises are an integral part of physical culture and a healthy lifestyle
to form a fully developed and physically prepared person
helps. Exercise with weights increases the body's aerobic and anaerobic capacity
increases, reveals a large number of reserve capillaries, the circumference of the chest,
lung capacity, dynamometry indicators (arm strength) and physical
to significant development of qualities, reduction of fat content and structure of muscles
helps increase the number of parts.

In a living organism there are always many different reactions. As a result,
all cellular structures are renewed. These changes happen a million times faster than in living
nature.

It is known from the literature that Na+
/K+
- ATPase - animal tissues
is an enzyme of the cell membrane, and in the case of using ATF energy, from the cell
the task of selectively expelling sodium ions and collecting potassium ions inside the cell
does. It is known from the literature that oaubain is Na+
/K+
-AFTase structure and its activity
Attenuator binds to α-subunit and vascular smooth muscle cells
Na+ by increasing the concentration of [Na+]in
/Ca
2+
- exchange system reversion function
based on [Ca
An increase in 2+ ]in causes an increase in the contraction force.

Anemia is a decrease in the amount of erythrocytes and hemoglobin in the
blood, which is a common disease. About 2 billion people in the world suffer from this disease.
Anemia is of the 2nd degree and is a sign or complication of various diseases. This disease is
mainly diagnosed in children and pregnant women.

In this article, we will examine various products that cause weight gain and
consider the reasons for their harmful effects on the body, the principles of healthy eating, and
their effects on the human body.

to prevent obesity, type 2 diabetes and cardiovascular diseases, it is
desirable to consume less food products containing glucose and maltose, because they
cause high and persistent hyperglycemia. In order to satisfy the craving for
carbohydrates, it is recommended to eat starchy products, because in this case,
postprandial hyperglycemia is less pronounced.

This article presents the author's opinion about healthy lifestyle and the need for it.
In addition, recommendations on lifestyle development have been developed

The stage of initial training of young athletes focuses on providing all-round
physical training, as well as emphasizing the need to purposefully educate volleyball-specific
movement skills.

Modern development of the educational process is characterized by the use
of various information technologies, which significantly change the strategy of education.

The article contains information about the general concepts of earthquakes,
their origin and causes, types, seismic regions and earthquakes that have occurred and their
consequences, and what to do when an earthquake occurs.

This thesis provides brief information about geological emergencies and
their types.

Our studies have shown that long-term reduction
level of physical activity under the influence of high temperature and insolation,
causes a significant reduction in energy consumption, which leads to a decrease in speed
synthesis of microergs, uncoupling of oxidation and phosphorylation, change in overall
gas exchange, decreased muscle strength and performance, and decreased function
muscle fibers, which is accompanied by a decrease in metabolism and activity
enzymes, the predominance of catabolic processes, a decrease in muscle mass,
loss of body weight and muscle strength.

This article provides information on the development, anatomy and
caecotrophy of the digestive system in growing rabbits. Elements of digestive anatomy and
feeding behavior in the rabbit, including caecotrophy. adapted to separate particles.

Nuclear energy and radioactive substances. Inspection methods. When
irradiated at a dose of 1 Gray. When irradiated at a dose of 2 Gray. When irradiated at a dose
of 4 Gray. Amount of amylase in liver tissue and blood.

After determining the true functions of blood and other genes, attempts to
explain the nature of temperament in other ways begin. At the beginning of the 20th century,
among doctors, there were those who connected temperament with the anatomical structure of
the body. They say that rich people are angry and stingy.
In fact, in most cases, cheerful people are plump, and impressionable, cold-hearted
people are thin. However, it can also be the opposite. There is no sufficient reason to say that
there is a connection between temperament.

It is aimed at studying the level of physical fitness and activity of women in
our country. The role of physical education in the physical abilities, health, and healthy lifestyle
of overweight women will be discussed.

Each distance acquisition takes place in different conditions and has its own
rules. The time to strike and defend depends on the distance between the opponents. The
shorter the combat distance, the faster and imperceptibly the blow will reach the target, and
the more difficult it will be to defend against it. The longer the distance, the easier it is for the
boxer to defend himself from his opponent's blows. For each distance there is a time limit that
determines the possibility of protection from blows. Female boxers have better conditions for
defense at long distance than at middle distance, and at middle distance than at close range.
Although it takes more time to perform actions at long range than at medium range, it is still
measured in seconds.

During the training macrocycle, the athlete's weight changes depending on
the dynamics of training. In a word, it is desirable to have self-control in sports. It is worth
noting that there is no blessing more important to every person than health. It is permissible to
appreciate it in time and live a healthy lifestyle.

Today, due to the widespread use of drugs in medicine, cases of acute
poisoning are common. In particular, the use of psychotropic drugs for self-medication is the
cause of household "chemistry" disease.

In this thesis; areas of temporary settlement of population; deadlines for
activities; procedure for removal in transport; information is provided on the organization of
public order and road safety on transportation roads.

In this article, the popularity of steroids in sports and athletes
in the middle of the year, its consumption is increasing, leading to various unpleasant situations
it is said that it is coming.

Physical culture is manifested in the harmony of material and spiritual values.
Sports facilities, sports equipment and supplies, sports clothes and
includes medical care. Spiritual values ​​of sports and games
interest, publicity, promotion and propaganda work, in mass media
lighting, activity of physical training and sports system, highly qualified athletes and
training system of Olympic reserves, international sports competitions of our compatriots
successes, in the organization of international sports competitions and events in our country
reflects.

Blood supply to the muscles plays an important role in the occurrence of fatigue. Due to
the constant contraction of the muscles in the same position during static work, their poor blood
supply causes rapid fatigue (for example, weight lifting). Fatigue in long-distance runners is
caused by a violation of control coordination between centers in the nervous system and
movement organs. Such fatigue is characterized by the weakening of heart contractions, the
increase in the number of contractions and, as a result, the decrease in the efficiency of heart
work. Therefore, the oxygen supply of the body decreases, the products of anaerobic
decomposition in the blood increase, and this situation, in turn, causes general fatigue.

According to modern concepts, the digestion of nutrients is a three-stage process,
including cavity digestion, membrane digestion and absorption [1]. Steroid hormones play an
important role in the regulation of these processes in a growing organism. It has been revealed
that many phytoecdysteroids also have a wide range of biological effects, which is manifested
in their pronounced regulatory effect on a number of physiological and biochemical processes
in organs and tissues

Analysis of foreign literature and local literature. Translation and editing of
foreign educational and scientific literature and use in the educational process, using the
experiences of foreign countries.

The thesis shows the changes in the amount of fats, phospholipids, cholesterol
and their moderation in liver injury, as well as the mechanisms of the liver's detoxification of
harmful substances.

The importance of athletics in strengthening the health of schoolchildren. The
processes of improving the health of schoolchildren through athletic training were analyzed.

Martial arts are actively developing in our country, which makes it urgent to
find ways to ensure the successful improvement of sports skills of highly qualified martial
artists.

Health is the greatest gift of god to His servants, and in most cases it is
not appreciated. When people understand how thier bodies are made and how they treat them,
they have a better chanse of preventing disease. With the help of this article, we will further
expand our knowledge about the anatomy and physiology of the spine, a perfect and complex
multitasking member of our body.

In the context of the introduction of innovative pedagogical technologies in
education, the physiological justification of the impact of stress on the ability of students to
perform physical and intellectual work is of urgent importance in the optimization of the
educational process [1].

In this thesis, brief information is given about environmental emergency
situations.

Prevention of fire and elimination of its consequences when it occurs
it is necessary for people to have sufficient skills. More so than in the past
we can observe that there are many fires in our country. Next
At times, fires mainly occur in production enterprises, shopping complexes and markets
We are witnessing what is happening. In the article population and commodity material wealth
fire and explosion protection measures, fire situation assessment,
there is talk about the presence of dangers and how to determine how they appear, fire
prevention recommendations are given. At the same time, the residents where the fire occurred and
measures for moving material assets are described.

This article discusses the role of national games in increasing
social activity of future physical education teachers. Opinions about their
benefits, harmful effects of placing different houses in social
networks in the formation of the younger generation.

There are people in this world who are only for themselves during their lifetime
they can build a statue that will remain in people's memory forever. From the sage:
"Who is the richest person in the world?" - when asked, he is "the richest man in the world"
his student is a great teacher," he answered. In the true sense, this is true. Generous
teachers produced good students," said the Russian scientist and mathematician
M. V. Ostrograusky. The works of good people and good teachers will last for several centuries
will be. One such person is a well-known scientist in his field, a humble teacher and a caregiver
leader, organizer, loving father, beloved grandfather of his grandchildren, Andijan State University
associate professor was Ergashboy Khalilov, candidate of biological sciences.

: Everything on earth breathes. Breathing (Latin: respiratio) is a set of processes
consisting of oxygen entering the body and carbon dioxide (CO2) leaving it, as well as the
release of energy necessary for the life of the body as a result of oxidation-reduction reactions
of organic substances using oxygen in cells and tissues.

Currently, the method of clonal micropropagation is the most widely used
used to heal plants infected with viruses. For successful
clonal micropropagation of plants requires a special complex
equipped premises, including rooms for sterilization of nutritional
environment and dishwashing; boxes for isolation, tissue transplantation and plant division;
thermostatic for growing isolated tissues on nutrient media and
obtaining regenerated plants; greenhouses for growing and propagation
mother plants.

The article analyzes the professional methods used by the pedagogue in the
technical-tactical and physical training of the athlete in the sport of wrestling. Also, thoughts
on the role of wrestling types, teaching of general developing and special exercises in wrestling
training, teaching techniques and rules of a specific type of wrestling, and the development of
qualities are brought to the fore.

Action games are widely used in primary school classes. Movement games in
these classes serve to improve and strengthen movement skills developed in physical education
classes. If the main part of the lesson consists of game materials related to the implementation
of a specific task, for example, teaching the basic elements of a basketball court, in its
introductory part, action games such as "Ball race" can be used. In such cases, "Hunters and
ducks" and "Shooting" games are included in the main part of the lesson. Games that are
unfamiliar to children should not be included in the lesson.

Murabbiy tomonidan amalga oshiriladigan boshqarishning psihologik –
pedagogik vositalarini ko’rib chiqayotib, ularning asosiylari ishontirish, tushuntirish,
singdirish kabilardan iborat ekanligini anglaymiz. Sportchilar pisihologik va pedagogic
tarbiyani faqatgina murabbiylaridan emas o'zlarining yashash sharoitlaridan kelib chiqan holda
yani o'z oilasi, yaqinlari, do'stlari tas'irida ham tarbiyalanadilar.

Women's health is the most important problem of society. The birth of a
healthy child depends primarily on his health. In this case, the issue of women's health was
considered.

Cardiovascular disease (CVD) remains the leading cause of death
globally, highlighting the urgent need for sustainable and accessible preventative and
therapeutic approaches.

Accidents that occur at radiation-hazardous facilities, nuclear power plants,
customs facilities, nuclear waste and radioactive material storage facilities pose a serious threat
to the health and life of facility workers and residents living around the facility

The thesis is devoted to the study of the physiology of respiratory regulation
in humans. The paper discusses the basic mechanisms that control breathing, including the role
of chemoreceptors and mechanoreceptors, as well as control centers in the brain.

In the article, mitochondrial membrane permeabilization is important in cell
death by apoptosis or necrosis. Most of the signals leading to cell death arrive at the
mitochondria, for example, Bcl-2 proteins such as Bid and Bad are involved in this process.
Different ways of new formation of internal signals of the cell lead to activation of the
caspase system, increase in the concentration of Ca2+, nitrogen (II) oxide, amphipathic
peptides and ceramides in the cytosol, directly or indirectly, changes in mitochondrial ion
permeability.

this article discusses the interaction of hypokinesia and gamma rays on the body
and various diseases and changes observed in the body as a result of these effects

Smooth muscle cell sarcoplasmic reticulum (SR) Ca
2+
-transport systems, i.e.
ryanodine receptor (RyR) and inositol-1,4,5-trisphosphate receptor (IP3R) and Ca
2+ -ATPase
(SERCA) mainly SMHs are important in regulation of Ca
2+ homeostasis becomes important
[1; pp. 50-86; 2; pp. 266-286]. Through its activity, SERCA is involved in Ca
2+ homeostasis
and reduction of intracellular [Ca
2+
]i concentration. Also, through SERCA, the concentration
of Ca
2+
ions is reduced and causes relaxation of smooth muscle cells [3; pp. 84-93]. IP3R
receptors - or ryanodine receptors (RyR) - are channels that ensure the release of Ca
2+
ions
from the SR to the cytosol [4; pp. 2-9]. Taking into account the above information, the purpose
of this study is to study the mechanism of sarcoplasmic reticulum ryanodine receptor activation
during the relaxant effect of 1,2,6-tri-O-galloyl--D-glucose (GT-2) hydrolyzable tannin on
aortic smooth muscle preparation. consists of

The purpose of writing a scientific article is to improve the selection
methodology of young handball players, to analyze and develop recommendations for the
development of the priority skills specific to handball sports. Through the national dynamic
games, it is planned to develop the qualities of agility of the students playing handball, and the
pedagogical skills and health of the players are monitored.

It is permissible to list movement techniques, volitional qualities, sports
techniques and volleyball tactics, as well as instilling instructor skills as special tasks of
teaching. To perform the assigned tasks, the athlete must have a high level of physical,
technical, tactical, mental, theoretical and game (integral) training

From a physiological point of view, changes in the functional status of elderly
people and the reduction of drinking capacity depend on many factors. First of all, the speed
of blood movement slows down in them, the capacity of circulating blood and its oxygenation
decrease, hypoxia develops in tissues and organs

It is known that heredity has a great influence on the development of the
human organism. This source contains information about the storage of genetic information in
the genome structure of the organism, as well as biotic and social factors.

Currently, there are a number of infectious diseases, and it is very important to
learn and know about them. Any infectious disease will cause an epidemic if it breaks out. An
epidemic is a widespread spread of infectious diseases in a country, region or country. In this case, the
number of patients will be 5-10 times more than usual

New to teaching science
use of pedagogical technologies; teacher training and teaching, as well as available
is a person responsible for the effective use of opportunities and conditions. This task
to perform the teacher training process and the scientific and technical subjects taught
he should know all aspects. The purpose of this is that the teaching method is in this way
so that students can fully master the taught subject

In this article, sports for the future of the young generation in our country
there is talk about the attention being paid, and this information is the necessary literature
explained using

In our country, the preservation of human health and a healthy lifestyle among the population is widespread
issues of promotion have long been given great attention at the level of state policy. Uzbekistan
Action strategy for these issues in the development of the Republic Five
we can give examples of initiatives and several decisions and orders.

During the training macrocycle, the athlete's weight changes depending on
the dynamics of training. In a word, it is desirable to have self-control in sports. It is worth
noting that there is no blessing more important to every person than health. It is permissible to
appreciate it in time and live a healthy lifestyle.

This article provides information on the study and analysis of oxidative stress
indicators in the blood of obese type 2 diabetes patients, the role of oxidative stress in type 2
diabetes and the evaluation of these indicators.

This thesis is devoted to the topic of the influence of toxic metals and their
effect on the human body. The term metals, sources and releases into the environment, and
their general characteristics are considered.

This thesis addresses the issue of the influence of proper nutrition and fast
food on the human body. Examples of products such as chips, hot dogs, hamburgers on vital
human organs are given.

It is known that for many years, in the conditions of stable social
relations, attitudes towards institutions of society such as education and science have
been formed in a unique way. For example, during the time of the former union, no
member of society was suspicious of the activity of an educational institution or
scientific organization, and did not have a biased attitude towards the activities of its
subjects. Now, not only in Uzbekistan, but also in the whole world, there is a tendency
to distrust any social institution.

Abstract: Self-education is a specially organized, independent, systematic cognitive
activity aimed at achieving certain personally or socially significant educational goals:
satisfying cognitive interests, general cultural and professional needs, as well as advanced
training

the article reveals modern methods of teaching biology. Many biological
processes are complex, and the use of information technology to create an image of biological
processes in students is highlighted. Multimedia animated models allow you to imagine and
understand biological processes and work independently.

In the last years of the 20th century, the type and quantity of man-made
emergency situations related to human activities are increasing, but it is necessary to have a
complete picture of emergency situations, to prevent them as much as possible, to reduce their
damage as much as possible, and to effectively protect our citizens. measures to be achieved
are considered and highlighted.

The project method of teaching is introduced into the educational process.
The leading specialists of enterprises and organizations are involved in the process of
evaluating students' knowledge, preparing course projects, conducting diploma theses based
on the order of enterprises, jointly holding science Olympiads, awarding famous scholarships,
and issuing relevant qualification certificates.

Diseases of the cardiovascular system are the leading causes of disability and disability in the world to date
remains the main cause of death. World Health Organization
according to data, 56% of all deaths are caused by diseases of the cardiovascular system
caused by Cardiovascular diseases in European countries are 4.3 million per year
(48%) causes the death of the population.

The primary mechanism of nitrite toxicity is iron oxidation. That is, the iron
(Fe2+) in hemoglobin changes to the valence state of iron (Fe3+) to form methemoglobin. It
is known from the literature that as a result of the formation of methemoglobin, disturbances
are observed in the process of oxygen delivery to human tissues and cells.
As a result, an opportunity is created for the development of various pathological
conditions in the body. We can say that the poisoning of the body with nitrites depends on the
proportion of metagemoglobin in the blood. In recent years, scientific researches have proved
the increase of nitric oxide in the blood in the etiology of human cancer.

This article describes the cardiovascular system, its structure, function and
main tasks. Also, the article contains ideas about the fact that diseases of the cardiovascular
system have become an urgent problem today. Information about their natural and artificial
treatment has been provided.

According to the analysis of the above studies, vincanine and pyrazoline
alkaloids have strong cardioprotective properties and effectively eliminate the disturbances in
papillary muscle contractile activity caused by hypoxia. It allows us to assume that this
function of the studied alkaloids mainly depends on the modulation of [Sa2+]in dynamics in
cardiomyocytes.

In the article, the essence, purpose, tasks of wellness technologies, as well as
the relevance and importance of wellness technologies in physical education and sports in the
formation of a healthy lifestyle today.
The functions of physical movement in improving the system of physical education and
wellness activities of students of pedagogical higher educational institutions and improving
the work productivity of students during the day, mentally and physically, have been
scientifically substantiated.

The analysis of the training activity of short-distance runners during the
annual cycle allows us to come to the following conclusion. The developed training programs
were carried out almost completely. The training process was organized on the basis of the
laws of achieving the sports form previously developed for this indicator, deviations in the
analyzed signs of physical and distance training in the experimental groups correspond to the
indicators planned as "reasonable" dynamics.

What can be heart problems? Problems can occur in any part of the heart:
The muscles in the heart chambers can contract very weakly, which leads to heart failure.
When heart valves are diseased, blood can flow through the valves and back into the heart.

The article describes the regulation of the physiological systems of the
organism caused by excessive stress during the adaptation process, the factor that causes the
disruption of the adaptation process.

Protection of the population in natural and man-made emergency situations
is one of the main tasks of civil protection. For this reason, a scientific approach to protection
measures in the event of emergency situations in the regions, including general education
schools, is one of the urgent issues of today [1].

Diet is a necessary and important thing that athletes should think about every day
is the issue. A diet that is full of valuable ingredients - for all sports
provides high performance. Whatever you eat, act accordingly
you can Before sitting down to the table to eat, they are athletes of all kinds of sports
knowing how much energy your training routine is expending and that energy
the amount should be arranged in food.

In this article, a healthy lifestyle and the need for it in life
comments by the author. In addition, lifestyle
development recommendations have been developed.

Any social, material,
not just because a spiritual thing or event has acquired positive significance in the past
because it is able to create new opportunities for future prospects
called value. More precisely, values ​​are necessary for society and spiritual development
is a product. The role of scientists in instilling this in the spirituality of young people is invaluable.

Well-known sources of Pb emissions include smelting and mining, batteries,
pigments, and ceramics. The accumulation of this metal in the environment and its nonbiodegradability have increased the risk of exposure to humans. The main routes of exposure
to Pb are ingestion and inhalation due to its presence in food, air and tobacco leaves. The World
Health Organization (WHO) has announced 10 chemicals or groups of chemicals that pose a
risk.

The availability of a large amount of data in the specified direction has made
it possible to conduct a small number of studies on the effect of pancreatic proteolytic enzymes
on pancreatic secretion. The main task of these experiments was to present the principle of the
corrective action of duodenal enzymes, to summarize the selective nature of these effects and,
if possible, to show the differences between the effects of zymogenic and activated enzymes.
proteinases.

This thesis provides comprehensive information on psychotropic substances,
highlights the problems associated with their use, and suggests possible solutions.

This article analyzes the physical training of young people, as well as the effect
of physical exercises on the human body, and provides information about the need for physical
development.

Physical qualities, movement skills and skills, especially coordination skills,
have an inestimable role in increasing the level of health and professional-practical physical
fitness of students studying in various fields of study, including professionals working in
various professions. it is.

In this study, the vital capacity of the lungs of the 5th-6th-7th graders of the
sports school No. 1 of the Paxtoabad district of Andijan region was analyzed on the basis of
comparison. Generally accepted anthropometric research methods were used in the research.

This article deals with the constant addiction to psychotropic substances
among people today. Information about the development of various diseases due to regular
consumption is given.

Today, our society, the development of science and mass media, the
emergence of new techniques and technologies, on the one hand, improve the quality of life,
and on the other hand, increase the risk of large-scale disasters and catastrophes (emergency
situations).

That uncomfortable condition begin effecting live organisms,
namely human beings [2]. According to toxicity, lead among different xenobiotics is concluded
to be sharp. After lead enters to organism of human, it begins affecting to diverse systems of
organism by breaking down. For example, encephalopathy with lead appears in body when
lead affects to cardiovascular system.

: In this article, development means the processes of quantitative and qualitative
changes observed in the human organism, which call for an increase in the complexity of the
levels of organization of all its systems. Development includes three main factors; growth,
differentiation of organs and tissues, formation (acquiring an organism-specific and monad
form). These factors are interrelated and complement each other.

Nuclear energy and radioactive substances. Inspection methods. When
irradiated at a dose of 1 Gray. When irradiated at a dose of 2 Gray. When irradiated at a dose
of 4 Gray. When irradiated at a dose of 6 Gray. Amount of amylase in salivary gland tissue and
changes in blood.

On the basis of the obtained experimental results, it can be assumed that the
relaxant effect of the extract of fennel is due to the blocking of the potential-dependent Ca2+
channels located in the sarcolemma of smooth muscle cells and the reduction of the entry of
Ca2+ ions into their cytoplasm.

the development of coordination skills of young rhythmic gymnasts is more
effective through the following exercises. This helps young athletes to successfully perform
exercises and achieve good results during competition.

Currently, in sports, various indicators are used to optimize the content of
training programs. Combat sambo is a developing type of mixed martial arts, in which the rules
of the competition allow the use of a large variety of technical-tactical actions (TTH) and their
combinations with the use of striking and wrestling techniques. Success in combat sambo
competitions is ensured by the effectiveness and efficiency of the technical and tactical actions
of the athletes. Compared to single-strike movements, combined TTH has been found to
increase the size, efficiency and effectiveness of the athlete's arsenal of technical-tactical
movements, and mastering combinations with the use of striking fighting techniques creates a
great potential for successful competition. Currently, in sports, various indicators are used to optimize the content of
training programs. Combat sambo is a developing type of mixed martial arts, in which the rules
of the competition allow the use of a large variety of technical-tactical actions (TTH) and their
combinations with the use of striking and wrestling techniques. Success in combat sambo
competitions is ensured by the effectiveness and efficiency of the technical and tactical actions
of the athletes. Compared to single-strike movements, combined TTH has been found to
increase the size, efficiency and effectiveness of the athlete's arsenal of technical-tactical
movements, and mastering combinations with the use of striking fighting techniques creates a
great potential for successful competition. 

This thesis describes the structure of the eyes of children and their difference
from the structure of the eyes of adults, as well as age-related features of the structure of the
eye.

In this research, the value of hand strength (right hand and left hand) of
students of the 48th general school in Altinkol district of Andijan region in the 5th-6th grade
was analyzed and physical indicators have been studied.

Currently, the development and testing of an integrated system of lessons, where the
establishment of connections between common concepts for a number of subjects is a psychological
and methodological basis, is of urgent importance. At the same time, interdisciplinary relations should
be taught at the level of the curriculum and provided with the necessary teaching tools.

"Athletic gymnastics" for students of physical education in schools, lyceums and colleges
students with various disabilities in education, as well as in their health
in restoring health, educating young people in the spirit of patriotism, healthy lifestyle
may have an effective role in implementation

In the article, training session for physical training of young football players
these should be taken into account in the proper organization of work, active in sports training
use of games and development of physical qualities.

Move the muscles
Each of the excitatory nerve cells, i.e. motoneurons, has tens and
connected by hundreds of muscle fibers. Where the nerve fiber meets the muscle fiber
are special plates consisting of a thin membrane, which are called synapses. Motoneuron, his
fiber and the muscle fiber connected to it together form a muscle-nerve movement unit
does.

The relevance of environmental pollution with heavy metals on a global scale
is primarily explained by the fact that such harmful salts are widely accepted by the human
body and cause great harm to health. Heavy metal salts affect all systems of the body and are
toxic, allergic, carcinogenic, and gonadotropic.

Almost every one of us in childhood wanted to know whether “living” and
“dead” water really exist, and where these magical liquids come from in order to collect at
least a few drops and use them in our lives when needed. But it’s not for nothing that people
say: “The fairy tale is a lie, but there’s a hint in it!” A lesson to good fellows!”

Studying the composition of the valerian plant revealed that it is rich in
flavonoids. Therefore, we came to the conclusion that it is appropriate to create a new food
additive with fewer side effects using the field plant and to use it in diabetes and cardiovascular
diseases.

Health and fitness are the main indicators of human physical maturity and
ensure the full functioning of the body and its organs in specific conditions. The achievement
of independence of our country opened the way for us to learn the historical content of our
national physical culture. Physical education makes it possible to mobilize the physiological
healing mechanism of the human body without drugs. In order to strengthen the health of our
people, a wide path has been opened for the use of physical education based on national
traditions. Our people understand very well that taking care of the offspring is a sacred duty
for the future of our people and country

The habit of breathing and exhaling through the mouth not only worsens the
supply of oxygen to the body, but also weakens the diaphragm and other muscles associated
with it. As a result, it has a negative effect on keeping the body straight.

Many people think that pain in the abdominal area is related to problems of
the musculoskeletal system or neurological in nature. This is completely wrong. Pain in the
kidney can spread to the abdomen

Earthquake is one of the most dangerous natural phenomena. Earthquakes
take the first place among natural disasters in terms of economic damage and human casualties.

This thesis provides brief information about hydrometrological emergency
situations and their types, as well as protection of the population and the territory from
emergency situations.

Currently, it is biotechnological in the fields of agriculture, animal husbandry and veterinary medicine
an excellent product of the industry - additional meat and milk using enzyme preparations
can be cultivated. Enzyme preparations included in the ration are used in living organisms,
help in better digestion of nutrients, especially when they are very young
will give. A bacterial gut that improves digestion in animals for research
prevention and treatment of diseases, energy value, efficiency of food
and created on the basis of local microorganisms that increase their productivity
local feed with probiotics, enzymes and rich in protein, replacing imports
suffix is ​​selected.

The article discusses the morphological indicators of physical
development of female students in the modern developing world. The specifics of this
competencies in the structure of a teacher’s professional work.

The level of free radicals in the cell is controlled by complex antioxidant
defense systems. As a result of LPO of the mitochondrial membrane under conditions of
oxidative stress, its permeability can also change. In this case, the process of mitochondria
collapse is observed, which causes a sharp increase in the permeability of the megachannel
(mPTP). In this case, the realization of mitochondrial suppression was also confirmed in
experiments. OS-related mitochondrial dysfunction can be inhibited by various bioactive
agents. There are data on plant substances inhibiting mitochondrial dysfunction in various
pathological conditions. However, due to the lack of data on the effect of isoquinoline alkaloids
on heart mitochondria, the following experiments were conducted

The human body is always under various influences of the external
environment. The body adapts to the external environment during life. Most of them are
necessary for the normal reactions of the body. A living organism has the ability to resist
unnatural influences. The body’s protective mechanisms are not always able to fulfill their task
and cannot overcome the harmful effects of influences. In such cases, the functions of the body
are out of control. Disruption of the morphological structure occurs and the person becomes
ill. Through this article, we will give you a brief overview of spine related diseases and their
causes

In this graduation work, the subject of “physiology of human and animals”
“application of interactive methods in the coverage of the topic of physiology of the endocrine
system” and the physiological processes in it the location of the glands of internal secretion
and their structure have a step-by-step effect on the body of hormones secreted from the gland,
taxiles. In this work, a comparative analysis of local and foreign literatures was analysed, on
the basis of which the necessary quality and elements of the textbook were determined, which
are most important for the effective assimilation of material. On the basis of the results of the
study, a conclusion was made, which was obtained in. Scientific sources, as well as special and
foreign literature on the physiology of Man and traitors were also cited in the coverage of the
topic

In this research work, the physical development of young students studying at
the Faculty of Physical Culture of Andijan State University is described. Also, opinions on the
role and importance of belt wrestling in our country are studied.

In the conditions of training boys aged 14-18 years with a greater amount of
professional training in specialties that require intense labor, the existing regime of physical
exercise does not provide normal rates of development of motor function, does not stimulate
an increase in the functional capabilities of the body and an increase in the overall performance
of students.
From this it is possible to draw the following conclusions; therefore, this regime cannot
ensure the full implementation of the main tasks of physical education for young students.

In this article, biomechanical parameters (force, speed, time) are quantitative
evaluation of the speed of manifestation of one or another quality. The reasons why all the
versatility of human movement capabilities can be described by the following movement
qualities, i.e.: strength, speed-strength, agility, endurance, flexibility, are explained through
interactive methods.

In this research, the value of hand strength (right hand and left hand) of
students of the 48th general school in Altinkol district of Andijan region in the 5th-6th grade
was analyzed and physical indicators have been studied.

methodological approaches to teaching the academic discipline "Life safety"
are considered. Various methods and means of organizing educational activities and practical
exercises using situational problem solving, working in small groups, and the "brainstorming"
method are discussed.

The article discusses the development of physical qualities in the lessons of
physical education and physical development of children, various exercises are used.

This thesis addresses the issue of the influence of proper nutrition and fast
food on the human body. Examples of products such as chips, hot dogs, hamburgers on vital
human organs are given.

It is known that in the life of mammals, lactotroph is clear from nutrition
the transition to nutrition is crucial. Incoming food at this time
Significant changes occur in the quantity and quality of substances
determines the direction of further development of the organism.

Water, which a person uses not only for drinking, but also in other areas of his
life, has a lot of different properties. In addition, water can have specific energy that is
beneficial or harmful to humans. Using a modern method of influencing the composition and
properties of water - electrolysis - it is possible to obtain a liquid endowed with positively or
negatively charged ions from ordinary water. This is the so-called living and dead water.

According to available data, the normal function of blood vessels is ensured
by the activity of various ion transport systems located in the membrane of blood-vascular
smooth muscle cells and in the sarcoplasmic reticulum [1,2]. It was noted that potentialdependent Ca2+
-channels located in the plasmalemma play an important role, and Ca2+-
transport systems are one of the central components in the contraction function of smooth
muscle cells [3]. Taking into account the above information, the purpose of this research work
is to study the mechanism of relaxant effect of 2,3-di-O-galloyl--d-glucose (GT-3)
hydrolyzable tannin.

In the course of the training, the teacher-coach should have a good understanding
of the three main teaching methods, what and how to teach the children consciously and fully,
and how to achieve the acquisition of practical skills and skills. If children's athletics exercises
are carried out continuously during training, like adult exercises, they will lose interest in this
sport and may not get the results we want.

The new tasks of the development of the educational system in the world
correspond to each new stage of the development of society. In many countries of the world,
physical education classes in the preschool education system, physical education and sports
activities in general schools have not become a necessary need for maintaining and
strengthening children's health and increasing their physical fitness.

When educating preschool children, the future teacher should look at the
children with confidence, properly reward their hard work, independence, initiative and create
an opportunity for them to work independently

In this study, the indicators of breath retention after taking a deep breath and
exhaling deeply were measured and analyzed in the 5th and 6th grade students of the 53rd
general education school of the Asaka district and the 35th general school of the Andijan
district. . The results obtained during the study were compared.

In this thesis man-made emergencies, their description and classification.
Causes of man-made emergency situations. Brief information about the protection of the
population and the territory from emergency situations will be given.

Human activity, including sports, is a certain quality
characterized by indicators. The main physical qualities include muscle strength, speed,
include endurance, agility and flexibility. Some authors describe a person as a speed-strength quality
also includes the main physical quality.

Embryonic development of rat submandibular and sublingual glands. Main saliva
structural features of glands. Salivary glands by the autonomic nervous system
to be innervated. Secondary innervation is myoepithelial cells.

Cardiovascular diseases affect human life and health on a global scale
are the main causes of morbidity and mortality. Functional after ischemic conditions
great efforts have been made to improve recovery and reduce infarct rates. Such
without, natural products, especially the secondary metabolites of plants protect the heart
It is an important task to identify new drugs with a therapeutic effect [Atanasov]

Modern technology has revolutionized the field of education and their
Integrating biology lessons into student learning and engagement with the subject
able to change methods. This scientific article organizes biology lessons
effective use of modern technologies in education, their students
activity, impact on conceptual understanding and practical application of biological concepts
attention is drawn. It is related to the use of modern technologies in biology education
exploring the benefits and challenges, this article is about their successful implementation
provides insight and creates a dynamic and immersive learning experience for teachers
gives recommendations on optimizing their use.

Reflexes are a reaction of the organism to the stimulation of receptors by the
central nervous system of the internal or external environmental factors. According to him, the
activity of the higher nervous system is different from the activity of the basic nervous system
aimed at maintaining the stability of the internal environment. Nerve connections that ensure
the activity of the higher nervous system are formed after the birth of the child. This activity
consists of the function of the cortex of the large hemispheres of the brain and appears on the
basis of unconditioned reflexes during human life.

In this article, the teacher distributes the text to the students, explaining the
essence of the new topic; Students get to know the text individually and express their personal
views through special symbols. When working with the text, students are advised to use the
following special characters: "?", "+", "v", "-"

n mitochondria of brown adipose tissue, it has been studied the oxidation
of various substrates, including NADH and ascorbate + cytochrome c, and determined the
activation of Mg2+
-stimulated ATPase. It was revealed that NAD-dependent substrates
(pyruvate + malate, glutamate) are oxidized with a high level of V4 and low RC. However,
on such substrate as succinate, it was detected a higher V4 rate and a lower RC than the
oxidation of NAD-dependent substrate. As well, high oxidation rates of exogenous NADH
and ascorbate + cytochrome c were detected, not coupled with the ATP synthesis. At
application of GDP, it was found a decrease in the respiration rate of V4 on succinate, on
NAD-dependent substrates as well as on the NADH substrate.
At the same time, liver mitochondria have been studied, that have mildly expressed
uncoupled respiration at oxidation of NADH, ascorbate + cytochrome c and other substrates.
In mitochondria of adipose tissue, it was found a high activity of Mg2+
-stimulated
ATPase, sensitive to oligomycin. It has a higher activity than DNP-stimulated ATPase.
In liver mitochondria, it is detected a significantly lower level of exogenous NADH
oxidation as well as Mg2+
-stimulated ATPase than in mitochondria of brown adipose tissue.
The intensive oxidation of exogenous NADH and ascorbate (+ cytochrome c), as well
as high activity of Mg2+
-stimulated ATPase, detected in mitochondria of brown adipose
tissue are explained by the presence of a special membrane-porous subpopulation of
mitochondria in suspension. This subpopulation, that exists separately from the ATPsynthesizing population of mitochondria, is capable of carrying out intense proton leakage
and tissue thermogenesis.

Each type of preparation has its own leading factors, with the help of which
the desired goal is achieved. At the same time, all types of preparations are inextricably linked.
For example, if a student is not physically well prepared, he will not be able to perform the
technique of attacking movements well. In this case, training the student from the physical side
requires many repetitions to improve the attack movements to a perfect level.

In the modern system of physical education, basketball occupies an
increasingly prominent place. This is explained by a number of reasons and, above all, the
effectiveness of sport as a means and method of physical education, its popularity, the
development and emergence of international sports relations, the steadily increasing general
cultural and prestigious significance of basketball in the modern world.

the article reveals modern methods of teaching biology. Many biological
processes are complex. Issues of biological education are in the center of attention in our
country, but also in many other countries

In order to prevent emergency situations and to reduce their losses as much
as possible when they occur, the heads of Civil Protection create special structures against
chemical, radioactive and explosion risks

The drug is a representative of cyclopyrrolones, a new class of psychotropic
drugs, structurally different from benzodiazepines and barbiturates. The sedative-hypnotic
effect of zopiclone is due to its high affinity to binding sites in the GAMK receptor complex
in the central nervous system.

This work is dedicated to the theoretical study of cognitive brain functions,
which represent a set of higher mental processes that enable the understanding of the world
and interaction with it. The paper examines the main cognitive functions, such as: attention,
memory, thinking, perception, and decision-making.

In this article, various xenobiotics affect the human body, several changes
occur in the pancreas, as a result of which diabetes is an important aspect. and more obesity
and it is called NOD (non-obese diabetic). And autoimmune diabetes develops independently
in these NOD rats.
According to the period of use, α-amylase activity of pancreatic homogenate was
determined in each rat in all groups, and the dependence of α-amylase ratio on specific tissues
was studied. According to the above table, α-amylase activity increased accordingly; 50.3%,
36.5

This article discusses hypokinesia of internal organs, consequences and their
treatment. Hypokinesia and physical inactivity are often considered synonymous words, but
there are differences between them. Thus, physical inactivity is a consequence of prolonged
hypokinesia and manifests itself in the form of a decrease in muscle strength. In itself, it occurs
due to a forced decrease in physical activity, for example, during a period of bed rest, a
sedentary lifestyle, or due to professional characteristics

This article describes the groups of muscles, their structure, important
functions, as well as the excitability, transmission, contractility, elasticity, plasticity,
contractility, tonicity and automaticity of smooth muscles.

There are different approaches to fighting in single combat sports and
understanding the style of fighting. Important concepts that determine the place and
importance of the concept of "competition style", as well as concepts that allow to clarify the
definition of this term - these are the concepts of tactics and strategy. Tasks of competition
tactics - to determine the result of actions in the fight against a certain opponent. To develop a
competition plan, it is necessary to set a goal, as well as determine the ways and means of
achieving it, taking into account the previously developed competition tactics.

The means of exercise therapy are therapeutic factors of influence, such as
gymnastic exercises, physical exercises in water, walking, exercises on exercise
machines.Forms of treatment with physical exercises: morning exercises, therapeutic
exercises, breathing exercises, mechanotherapy, measured walking, gymnastics on gymnastic
balls, therapeutic swimming, hydrokinesitherapy, occupational therapy.

Healthy physical development of children, preservation of educational
activity and working ability at a high level, organization of disease prevention is one of the
urgent problems. To solve them, it is important to study the physical development of the
population depending on the environmental conditions.

In this thesis, there are recommendations on the implementation of speed and
agility qualities in students who organize physical education classes in schools.

A chemical accident is a violation of technological processes in production,
pipelines, tanks, chemical storage warehouses and chemical toxic substances, leading to the
release of highly toxic substances into the atmosphere in quantities that pose a threat to human
life and health, the biosphere. is damage to transport vehicles [1].

Education each stage is defined by its own and some leading concepts. Only
only if the tasks are sequential, the teacher can correctly implement the educational method, including the use of educational principles, training and guiding exercises, methods
can be used appropriately. The structure of the educational process - special tasks,
stable relationships of principles, tools and methods in the stages of education
occurs through